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Revita™

 
 
 
 
 
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Revita is an intact human placental membrane allograft that preserves all layers of the biologic tissue and maintains the physiologic 3D architecture of the natural barrier membrane. 

What Revita Provides:

Revita provides the complete intact human placental membrane that is the physiologic tissue carrier naturally found in the body. This complete barrier containing amnion, intermediate layer and chorion retains many of the cytokines, growth factors, extracellular components, and cell communication signals the body uses to heal, protect and grow tissues.

 
 

What Makes Revita Different?

The preservation of the amniotic intermediate layer is a vital part of the membrane barrier present between the amnion and chorion layers. The intermediate layer:

  • Acts as a cushion
  • Contains Hyaluronic Acid (HA) + Collagen
  • Contains Growth Factors
  • Contains Glycosaminoglycans and Proteoglycans
 

Uses for Revita:

Clinical applications include:

  • Wound care
  • Orthopedics
  • Spine
  • Urology
  • Plastic Surgery
  • General Surgery
  • OB/GYN
  • Ophthalmology
  • Dental

 

 
 
 

Intact Human Placental Membrane vs. Dehydrated Competitor

Using the Clearify™ processing method, Revita preserves all three layers of the amniotic membrane architecture.

 
 
 

Unprocessed Placental Membrane

Revita Preservation of 3D Architecture

  • Freeze-dried
  • Never delaminated
  • Preserves intermediate layer which contains hyaluronic acid and additional proteins

Competitor

 
 
 
 

Revita contains many essential cytokines and growth factors:

(+) rating system range from 1-5 relative amounts present in the tissue

(+) rating system range from 1-5 relative amounts present in the tissue

 

Revita Sizes and Ordering Numbers:

 
 
 

Ascent™

 
 
 

Ascent is a minimally manipulated injectable amniotic fluid allograft designed to protect, cushion, lubricate, and reduce inflammation in fluid environments, such as joints and tendons. Ascent is processed using the patent-pending Selectify™ process that selects key amniotic fluid components and preserves the allograft in a shelf-stable format. The key benefits of Ascent are essential for tendon and joint relief:

 
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How does Ascent work?

Many different biomolecular functions trigger the inflammation and degeneration of joints and tendons. Decreased proteoglycan content, increased inflammation and anabolic factors, and increased degradative enzymes all contribute to hypertrophy. In many synovial joints, this results in cartilage degradation, a decrease in type II collagen, and fibrillation and osteophytes.2,3 Following rehydration, several components in Ascent help provide lubrication and reduce inflammation in these degenerative environments.


Injection Comparison

 
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Ascent contains hyaluronic acid, cytokines, and growth factors:

 

Ascent Sizes and Ordering Numbers:

 

For more information on Ascent, visit ascentinjection.com

1. Data on file 2. Goldring, et al. Inflammation in osteoarthritis. Curr Opin Rheumatol. 2011 Sep; 23(5): 471–478. 3. Goldring, et al. Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis. Eur Cell Mater. 2011 Feb 24;21:202-20.
 
 

 
 

Learn more about how Revita and Ascent are revolutionizing the amniotic tissue market.